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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASS4
All Species:
9.09
Human Site:
T483
Identified Species:
20
UniProt:
Q9NQ75
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ75
NP_001157588.1
786
87144
T483
I
D
A
I
H
R
S
T
D
H
I
E
E
S
V
Chimpanzee
Pan troglodytes
XP_001169779
786
87081
T483
I
D
A
I
H
R
S
T
D
H
I
E
E
S
V
Rhesus Macaque
Macaca mulatta
XP_001090515
786
86837
T483
I
D
A
I
H
R
S
T
E
H
I
E
E
S
V
Dog
Lupus familis
XP_534461
746
82524
I465
T
I
S
N
S
Y
Q
I
L
L
G
T
K
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q08EC4
804
88602
A481
I
H
R
I
R
R
A
A
D
H
V
E
E
S
V
Rat
Rattus norvegicus
Q63767
968
104244
V606
V
Q
D
L
K
A
A
V
A
A
V
H
G
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509857
821
90320
A513
I
D
E
I
H
R
A
A
D
H
I
Q
E
S
L
Chicken
Gallus gallus
XP_417499
814
90427
I505
I
E
E
I
H
R
A
I
D
H
I
K
V
S
L
Frog
Xenopus laevis
NP_001084484
853
95724
V494
L
E
D
I
H
K
A
V
D
S
I
I
A
S
L
Zebra Danio
Brachydanio rerio
XP_001341038
774
86396
N490
A
Q
R
L
T
D
S
N
L
Q
T
R
L
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782316
831
91548
C480
I
H
E
I
R
A
A
C
N
Q
L
K
L
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
93.6
64.2
N.A.
61
22.3
N.A.
51.4
43.4
38.5
29
N.A.
N.A.
N.A.
N.A.
23.8
Protein Similarity:
100
98.8
96
72.3
N.A.
71.5
38
N.A.
66.8
60.5
55.6
45.2
N.A.
N.A.
N.A.
N.A.
39.7
P-Site Identity:
100
100
93.3
0
N.A.
60
6.6
N.A.
66.6
53.3
33.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
13.3
N.A.
73.3
40
N.A.
86.6
80
66.6
13.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
28
0
0
19
55
19
10
10
0
0
10
19
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
37
19
0
0
10
0
0
55
0
0
0
0
0
0
% D
% Glu:
0
19
28
0
0
0
0
0
10
0
0
37
46
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% G
% His:
0
19
0
0
55
0
0
0
0
55
0
10
0
0
0
% H
% Ile:
64
10
0
73
0
0
0
19
0
0
55
10
0
0
0
% I
% Lys:
0
0
0
0
10
10
0
0
0
0
0
19
10
0
10
% K
% Leu:
10
0
0
19
0
0
0
0
19
10
10
0
19
10
28
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
19
0
0
0
0
10
0
0
19
0
10
0
0
0
% Q
% Arg:
0
0
19
0
19
55
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
10
0
10
0
37
0
0
10
0
0
0
64
19
% S
% Thr:
10
0
0
0
10
0
0
28
0
0
10
10
0
0
0
% T
% Val:
10
0
0
0
0
0
0
19
0
0
19
0
10
0
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _